Gastrointestinal Therapeutics Market Size & Share Analysis - Growth Trends & Forecasts (2023 - 2028)

Gastrointestinal Therapeutics Market Analysis

The gastrointestinal therapeutics market is expected to register a CAGR of 6.8% during the forecast period.

The COVID-19 pandemic created a worldwide disruption of supply chains, and the healthcare sector was affected badly. But the gastrointestinal therapeutics market showed a stable growth due to the correlation between Covid-19 and Gastrointestinal (GI) patients. A research study “COVID-19 and Gastrointestinal Disease: Implications for the Gastroenterologist”, published in Digestive Diseases Journal in March 2021, found that the digestive system may be affected by the SARS-CoV-2 virus, and those with the pre-existing disease are at greatest risk of adverse outcomes. Some repurposed drugs used against COVID-19 can cause or aggravate some of the COVID-19-related gastrointestinal symptoms and can also induce liver injury. In addition, according to the research “The mechanism and treatment of gastrointestinal symptoms in patients with COVID-19”, published in the American Journal of Physiology in August 2020, COVID-19 Cases with gastrointestinal symptoms are more likely to be complicated by liver injury and acute respiratory distress syndrome (ARDS), If these are not treated in time, coma and circulatory failure may occur.

The major factors that contribute to the growth of the gastrointestinal therapeutics market include the increasing prevalence of gastrointestinal diseases due to unhealthy dietary habits, additional numbers of clinical trials with accurate results, increasing healthcare expenditure, and growth in the geriatric population.

A wide range of new generation therapeutics is found targeting which includes novel small molecules and cellular therapy. Other driving factors include the rising surgical treatments and hospitalizations due to GI diseases and increasing R&D investments by biopharmaceutical companies in developing biologics and biosimilars. As of May 2021, there were around 6,443 ongoing clinical trials related to gastrointestinal diseases across different phases of development, as per the National Clinical Trial (NCT) registry. The positive outcomes from these studies can create new opportunities for effective therapeutics over the forecast period.

There is a rising trend towards the development of effective therapeutics products by the market players. The companies are majorly expanding their pipeline and product portfolio through collaborations with specialized companies in gastrointestinal therapeutics. For instance, in January 2020, Ayvakit (avapritinib) by Blueprint Medicines Corporation received approval from the US Food and Drug Administration (FDA) for the treatment of adults with unresectable (unable to be removed with surgery) or metastatic (when cancer cells spread to other parts of the body) gastrointestinal stromal tumor (GIST). Again, on May 20, Qinlock (ripretinib) tablets manufactured by Deciphera Pharmaceuticals Inc. received the US Food and Drug Administration (FDA) approval as the first new drug specifically approved as a fourth-line treatment for advanced gastrointestinal stromal tumor (GIST).

However, risk factors, such as those related to the physiological, behavioral, psychosocial, and socio-environmental aspects, restrict the populations from reporting the diseases early, which reflects the low awareness and the economic burden. These risk factors and the increasing number of patent expirations restrict the growth of the gastrointestinal therapeutics market.

Gastrointestinal Therapeutics Market Trends

This section covers the major market trends shaping the Gastrointestinal Therapeutics Market according to our research experts:

The Ulcerative Colitis Segment is Found to Witness a Healthy Growth Rate Over the Forecast Period

Gastrointestinal Therapeutics Industry Segmentation

As per the scope of the report, gastrointestinal disorders are medical conditions related to the digestive system that affect the colon, small and large intestine, and rectum. The disorders mainly include constipation, peptic ulcer diseases, and irritable bowel syndrome characterized by various symptoms such as pain, bloating, diarrhea, nausea, and vomiting. Gastrointestinal therapeutics include drugs, which are commercially available in the market, namely Aciphex, Afinitor, Akynzeo, Dificid, and Prilosec. Additionally, these disorders constitute a large proportion of outpatients and frequent hospital visits globally. The gastrointestinal therapeutics market is segmented by drug type (antacids, laxatives, antidiarrheal agents, antiemetics, antiulcer agents, and other drug types), dosage form (oral, parenteral, and other dosage forms), application (ulcerative colitis, irritable bowel syndrome, Crohn's disease, celiac disease, gastroenteritis, and other applications), and Geography (North America, Europe, Asia-Pacific, Middle-East and Africa, and South America). The report offers the value (in USD million) for the above segments.